Cancerous tumours of the bone

Last medical review:

A cancerous tumour of the bone can grow into nearby tissue and destroy it. It can also spread (metastasize) to other parts of the body. Cancerous tumours are also called malignant tumours.

Cancer that starts in the bone (called primary bone cancer) is rare. It is more common in children and young adults than in older adults (people over 40 years old). Cancer that spreads to the bone from other parts of the body (called bone metastases) is much more common in older adults.

Most bone cancers are called sarcomas. A sarcoma is a type of cancer that starts in connective tissue that surrounds and supports various organs in the body, including bones.

The following are sarcomas and other cancers that can start in the bones of adults.

Chondrosarcoma

Chondrosarcoma is a tumour that creates an abnormal amount of cartilage, which is the strong and flexible tissue that lines the joints. Chondrosarcoma can start in any bone that has cartilage, but it is most often found in the thigh bone (femur) or bones in the pelvis (hip). It can also be found in the shoulder blades, the cartilage of the trachea or larynx and in bones of the skull, spine, arm or ribs.

Chondrosarcoma is the most common type of primary bone cancer in adults. It is mostly found in adults over the age of 50. The different subtypes of chondrosarcoma are:

  • atypical cartilaginous tumour (also called low-grade chondrosarcoma)
  • secondary peripheral chondrosarcoma (which develops from a non-cancerous osteochondroma)
  • central chondrosarcoma
  • periosteal chondrosarcoma
  • clear cell chondrosarcoma
  • mesenchymal chondrosarcoma
  • dedifferentiated chondrosarcoma

Osteosarcoma

Osteosarcoma can start in any bone in the body, but it is most often found in the bones of the leg (femur or tibia) or the arm (humerus). In older adults, it may also be found in the bones of the pelvis, jaw or spine.

Osteosarcoma is the second most common type of primary bone cancer. It’s more common in children and adults younger than 40. It’s rare in people in their 40s, but found in people over 50.

Osteosarcoma is more common in people who have previously had retinoblastoma, Paget disease of the bone or radiation therapy treatments.

The different subtypes of osteosarcoma are:

  • low-grade central osteosarcoma
  • osteosarcoma not otherwise specified (NOS)
  • parosteal osteosarcoma
  • periosteal osteosarcoma
  • high-grade surface osteosarcoma
  • secondary osteosarcoma (cancer that develops when the bone is damaged by disease or radiation)

Ewing sarcoma

Ewing sarcoma most often affects the pelvis and the bones in the leg (femur or tibia), arm (radius, ulna or humerus), ribs, spine or skull.

Ewing sarcoma is the third most common type of primary bone cancer. It is very rare in adults over 40 years old and much more common in teenagers and young adults.

Find out more about Ewing sarcoma.

Chordoma

Chordoma is a low-grade cancer found in the base of the skull, the base of the spine (sacrum) or the other bones of the spine (vertebrae).

Chordoma is a rare tumour. It is more common in men than women and in adults over the age of 50.

Other cancers that can start in the bones

The following cancers can start in the bones, but they are not considered primary bone cancer:

Expert review and references

  • Michael Monument, MD, MSc, FRCSC
  • Kim Tsoi, BASc, MD, PhD, FRCSC
  • American Cancer Society. Bone Cancer. 2021. https://www.cancer.org/.
  • O'Donnell RJ, DuBrois SG, Haas-Kogan DA, Braunstein SE, Hameed M. Sarcomas of Bone. DeVita VT Jr, Lawrence TS, Rosenberg S. eds. DeVita Hellman and Rosenberg's Cancer: Principles and Practice of Oncology. 12th ed. Philadelphia, PA: Wolters Kluwer; 2023: Kindle version, chapter 61, https://read.amazon.ca/?asin=B0BG3DPT4Q&language=en-CA.
  • National Comprehensive Cancer Network. NCCN Guidelines for Patients: Bone Cancer. 2023.
  • Strauss SJ, Frezza AM, Abecassis N, et al. Bone sarcomas: ESMO–EURACAN–GENTURIS–ERN PaedCan Clincial Practice Guideline for diagnosis, treatment and follow-up. Annals of Oncology. 2021: 32(12):1520–1536.
  • American Cancer Society. Osteosarcoma. 2023. cancer.org.
  • American Cancer Society. Ewing Family of Tumors. 2021. https://www.cancer.org/.
  • Samuel LC. Bone and soft tissue sarcomas. Yarbro CH, Wujcik D, Gobel B (eds.). Cancer Nursing: Principles and Practice. 8th ed. Burlington, MA: Jone & Bartlett Learning; 2018: Kindle version, chapter 46, https://read.amazon.ca/?asin=B01M6ZZEWT&ref_=kwl_kr_iv_rec_1.
  • Augsburger D, Nelson PJ, Kalinski T, et al. Current diagnostics and treatment of fibrosarcoma – perspectives for future therapeutic targets and strategies. Oncotarget. 2017: 8(61):104638–104653. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732833/pdf/oncotarget-08-104638.pdf.

Your trusted source for accurate cancer information

With just $5 from readers like you, we can continue to provide the highest quality cancer information for over 100 types of cancer.

We’re here to ensure easy access to accurate cancer information for you and the millions of people who visit this website every year. But we can’t do it alone.

If everyone reading this gave just $5, we could achieve our goal this month to fund reliable cancer information, compassionate support services and the most promising research. Please give today because every contribution counts. Thank you.

Medical disclaimer

The information that the Canadian Cancer Society provides does not replace your relationship with your doctor. The information is for your general use, so be sure to talk to a qualified healthcare professional before making medical decisions or if you have questions about your health.

We do our best to make sure that the information we provide is accurate and reliable but cannot guarantee that it is error-free or complete.

The Canadian Cancer Society is not responsible for the quality of the information or services provided by other organizations and mentioned on cancer.ca, nor do we endorse any service, product, treatment or therapy.


1-888-939-3333 | cancer.ca | © 2025 Canadian Cancer Society