Signs and symptoms of childhood bone cancer

Last medical review:

Childhood bone cancer may not cause any signs or symptoms in its early stages. Signs and symptoms often appear as the tumour grows and causes changes in the body, such as a lump or a broken bone. Other health conditions can cause the same signs and symptoms as childhood bone cancer.

The most common symptom of childhood bone cancer is pain in a bone or joint that doesn’t go away or that keeps getting worse. Movement or activity may make the pain worse. The pain is often worse at night.

Other signs and symptoms of childhood bone cancer include:

  • swelling or a lump that can be felt over a bone
  • difficulty moving or using a limb (for example, limping when walking)
  • a bone that breaks unexpectedly (this may be because it is weakened by the cancer)

Expert review and references

  • Kriti Kumar, MD, MHSc FRCPC
  • American Cancer Society. Ewing Sarcoma. 2026: https://www.cancer.org/.
  • American Cancer Society. Osteosarcoma. 2025: https://www.cancer.org/.
  • Strauss SJ, Frezza AM, Abecassis N, et al. Bone sarcomas: ESMO–EURACAN–GENTURIS–ERN PaedCan Clincial Practice Guideline for diagnosis, treatment and follow-up. Annals of Oncology. 2021: 32(12):1520–1536.
  • O'Donnell RJ, DuBrois SG, Haas-Kogan DA, Braunstein SE, Hameed M. Sarcomas of Bone. DeVita VT Jr, Lawrence TS, Rosenberg S. eds. DeVita Hellman and Rosenberg's Cancer: Principles and Practice of Oncology. 12th ed. Philadelphia, PA: Wolters Kluwer; 2023: Kindle version, chapter 61, https://read.amazon.ca/?asin=B0BG3DPT4Q&language=en-CA.
  • Janeway KA, Randall RL, Gorlick R. Osteosarcoma. Pizzo PA, Poplack DG, eds.. Principles and Practice of Pediatric Oncology. 8th ed. Philadelphia, PA: Wolters Kluwer; 2021: 28: 3382—3484.
  • Lessnick SL, Grohar PJ, DuBois SG, Hogendoorn PCW, Davidson D, Laack NN, Dirksen U. Ewing sarcoma. Pizzo PA, Poplack DG, eds.. Principles and Practice of Pediatric Oncology. 8th ed. Philadelphia, PA: Wolters Kluwer; 2021: 27:3286—3381.

Your trusted source for accurate cancer information

With support from readers like you, we can continue to provide the highest quality cancer information for over 100 types of cancer.

We’re here to ensure easy access to accurate cancer information for you and the millions of people who visit this website every year. But we can’t do it alone.

Every donation helps fund reliable cancer information, compassionate support services and the most promising research. Please give today because every contribution counts. Thank you.

Medical disclaimer

The information that the Canadian Cancer Society provides does not replace your relationship with your doctor. The information is for your general use, so be sure to talk to a qualified healthcare professional before making medical decisions or if you have questions about your health.

We do our best to make sure that the information we provide is accurate and reliable but cannot guarantee that it is error-free or complete.

The Canadian Cancer Society is not responsible for the quality of the information or services provided by other organizations and mentioned on cancer.ca, nor do we endorse any service, product, treatment or therapy.


1-888-939-3333 | cancer.ca | © 2026 Canadian Cancer Society